Prior authorization has long been a symbol of administrative drag in U.S. healthcare—delaying care, frustrating providers, and increasing costs. Over 90 percent of U.S. physicians report that prior authorization causes delays in patient care—and nearly 90 percent say it contributes to professional burnout.1 Now, a sweeping CMS rule finalized in 2024 is set to upend the status quo. The Interoperability and Prior Authorization Final Rule (CMS-0057-F)2 doesn’t just mandate API adoption—it compels payers to reengineer how they handle requests, data, and transparency across the board.
The End of Manual Prior Authorization
For decades, prior authorization (PA) has relied on outdated methods—fax machines, phone calls, email threads—resulting in administrative waste and delayed care. In fact, nearly a quarter of U.S. physicians report that prior authorization has led to serious adverse events, including hospitalizations or life-threatening delays.3 The CMS rule marks the beginning of the end for these practices.
Announced in January 2024, CMS-0057-F mandates the adoption of modern, API-driven infrastructure to automate and streamline PA and health data exchange. The rule applies to:
- Medicare Advantage organizations
- Medicaid and CHIP (both FFS and managed care)
- Qualified Health Plans (QHPs) on the Federally Facilitated Exchanges
Commercial plans are not currently included; however, the rule is expected to influence broader industry standards over time.
What the Rule Requires: From Compliance to Capability
By January 1, 2027, payers must move from fragmented systems to a unified, API-driven infrastructure as required by CMS’s final rule. At the heart of this transition is the adoption of FHIR-based APIs, which will transform prior authorization from a manual, siloed process into an interoperable, fully digital workflow.
The rule mandates several APIs designed to create seamless data exchange across the healthcare ecosystem. Providers will be able to electronically submit prior authorization requests, check documentation requirements, and receive real-time updates or decisions—eliminating the need for faxes, phone calls, and disconnected portals. To further streamline care delivery, in-network providers must also be granted digital access to a patient’s claims, encounter, clinical, and prior authorization history—empowering them to make informed decisions at the point of care.
In addition, payers must support secure, automated data sharing both with other payers and with patients. When members switch plans, their clinical and prior authorization data must move with them, ensuring continuity of care without administrative delays. Patients themselves will benefit from expanded access to their own health and prior authorization data, promoting transparency and enabling them to engage more actively in their care decisions.
New Timelines. New Pressures.
The rule does not just digitize prior authorization—it accelerates it. Urgent requests must be resolved in 72 hours, standard requests within 7 calendar days. Every denial must include a specific, actionable reason. Additionally, beginning in 2026, payers must publicly post prior authorization metrics on their websites, such as approval/denial rates and average turnaround times. This means internal inefficiencies will soon be externally visible, putting reputational pressure on payers to perform.
These are not just technical deadlines; they are operational mandates that affect staffing, workflows, and long-term scalability.
A Mandate for Real Interoperability
Under the hood, this rule is about much more than prior auth. It is part of a larger federal push to tear down data silos and create a healthcare ecosystem that behaves more like a modern, digital industry.
Payers must not only modernize systems but also:
- Align with USCDI (U.S. Core Data for Interoperability)
- Integrate with provider EHR systems using SMART on FHIR
- Track and document clinical decision logic in structured, shareable formats
- Enable secure, permissioned data sharing with third-party apps and provider organizations
This is not plug-and-play IT. It is a strategic replatforming of how payers operate at their core.
The Risk of Falling Behind
Payers who approach this rule as a checkbox exercise—focusing only on minimum compliance—risk more than regulatory penalties. They risk damaging provider relationships due to slow or unreliable PA workflows as well as public reputational harm via poor performance metrics. Further risks include losing market share to more tech-forward competitors; and an increased operational cost due to inefficient legacy systems and manual workarounds
In contrast, those who embrace the shift stand to gain significant advantages—lower administrative burden, faster service turnaround, and stronger provider alignment.
Turning Regulation into Transformation
To meet the demands of CMS-0057-F and thrive in an increasingly digital healthcare ecosystem, payers must rethink how their systems handle prior authorization and data interoperability—from the ground up. This means building scalable, standards-based APIs that support automated prior authorization submissions, payer-to-payer data exchange, and real-time access for both providers and patients. These APIs must be secure, modular, and capable of integrating with existing platforms—without introducing unnecessary complexity.
Modernizing prior authorization also requires full end-to-end workflow automation. From intake and clinical review to adjudication and provider notification, each step must be digitized and streamlined to meet strict CMS timelines without increasing administrative burden. This is especially critical in achieving the mandated turnaround times—72 hours for urgent requests and seven calendar days for standard cases—while maintaining accuracy and consistency.
Equally important is seamless provider integration. By connecting directly with provider EHRs and enabling SMART on FHIR capabilities, payers can reduce manual follow-ups and foster real-time, context-aware collaboration with clinical teams. This not only improves efficiency but also strengthens provider relationships, which will be critical as performance metrics become public and increasingly scrutinized.
Transparency must also extend to how decisions are communicated. Payers need systems that can generate clear, standardized denial reasons—structured in a way that supports both compliance and clinician understanding. Meanwhile, CMS’s public reporting requirements demand real-time visibility into operational performance. Intuitive dashboards, aligned with federal standards, can help internal teams monitor key metrics while also meeting external transparency obligations.
Finally, the underlying architecture must be built for more than today’s rule—it should lay the foundation for future regulatory shifts, data sharing innovations, and scalable interoperability across the healthcare continuum.
The Bottom Line
CMS-0057-F marks a pivotal shift in how payers must operate. Prior authorization can no longer remain a manual, reactive process. It must become real-time, interoperable, and patient-centred.
Mizzeto specializes in delivering precisely these kinds of solutions—combining automation, streamlined prior authorization, clinical care review capabilities, and a unified utilization management intake process. We help payers not only meet regulatory requirements, but also reimagine their core operations for greater efficiency, scalability, and long-term impact.
The payers who act now, those who build modern infrastructure, streamline workflows, and enable intelligent automation, will not just comply with the rule. They will gain a lasting advantage in an industry that is rapidly evolving.
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